Tyrosine-protein kinase ITK/TSK also known as interleukin-2-inducible T-cell kinase or simply ITK, is a protein that in humans is encoded by the ITK gene. ITK is 

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ITPKA Antibodies Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling.

ITPKA. Gene descriptioni. ITPKA Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, ITPKA Genome Browser, ITPKA References ITPKA - Explore an overview of ITPKA, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data. Itpka - Inositol-trisphosphate 3-kinase A - Rattus norvegicus (Rat) - Itpka gene & protein UniProtKB - P17105 (IP3KA_RAT) GuideToPharmacology Gene Category Name: Inositol 1,4,5-trisphosphate 3-kinases: GuideToPharmacology Gene Category ID: 280: Gene Biotype: PROTEIN_CODING Gene information about ENSG00000137825 / ITPKA - inositol-trisphosphate 3-kinase A Itpka MGI Mouse Gene Detail - MGI:1333822 - inositol 1,4,5-trisphosphate 3-kinase A. View mouse Itpka Chr2:119742337-119751253 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression. Home. Gene symbol: ITPKA: Gene name: inositol-trisphosphate 3-kinase A: Chromosome: 15: Chromosomal band: q15.1: Imprinted: Unknown: Genomic reference: NC_000015.9: Transcript reference: NM_002220.2: Associated with diseases-Citation reference(s)-Curators (1) Global Variome, with Curator vacancy: Total number of public variants reported: 3: Unique Despite recent advances in cancer therapy, the overall 5-year survival rate of patients with lung cancer remains low.

Itpka gene

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IP3-3KA, IP3KA. Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. ITPKA gene body displayed low or absent levels of methylation in most normal tissue but was significantly methylated in malignant tumors.

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Gene. Itpka. Species Mouse Transcripts. 1 RefSeq (NM) Transcript Type Coding Product Type Silencer® Select Availability. Made to Order. Catalog # 4390771 Standard | 5 nmol Price (USD): 324.00. Your Price (USD): Online offer (USD): Check

General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC.

Itpka gene

Gene Stat Angle Cell Pvalue Qvalue A1BG 0.588360560294644 Hela 0.309994275305751 0.517623048509169 ITPKA 0.525903245951374 

Predicted to localize to cytoplasm and nucleus. Orthologous to human ITPKA (inositol-trisphosphate 3-kinase A). ITPKA gene expression in Bgee. Gene: ITPKA - ENSCAFG00000009562 - Canis lupus familiaris (dog) NCBI Description of ITPKA: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling.

ITPKA gene body methylation regulates its expression and thus serves as a novel and potential biomarker for early cancer detection. 1991-11-01 Gene Expression: ITPKA [ NCBI-GEO ] ITPKA [ EBI - ARRAY_EXPRESS ] ITPKA [ SEEK ] ITPKA [ MEM ] Gene Expression Viewer (FireBrowse) ITPKA [ Firebrowse - Broad ] Genevisible: Expression of ITPKA in : [perturbations] BioGPS (Tissue expression) 3706: GTEX Portal (Tissue expression) ITPKA: … Official gene symbol, which is typically a short form of the gene name, according to HGNC. ITPKA (IP3-3KA, IP3KA) Tissue specificityi. The RNA specificity category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5.
Xlformulas xlvalues

Ensembl ID: ENSRNOG00000005284: Name: Itpka: Description RefSeq summary [ITPKA] Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.

Mapping By in situ hybridization, Erneux et al. (1992) mapped the ITPKB gene to 1q41-q43. Plasmid ITPKA_3xmScarletI from Dr. Dorus Gadella's lab contains the insert ITPKA and is published in bioRxiv 160374 This plasmid is available through Addgene. ITPKA gene, which is located in 15q15, encodes a predicted 461 amino acid polypeptide.
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Gene information about ENSG00000137825 / ITPKA - inositol-trisphosphate 3-kinase A

ITPKA gene, which is located in 15q15, encodes a predicted 461 amino acid polypeptide. Under physiological conditions, ITPKA is only identified in neurons and testis [ 6 ]. Plasmid pCNL-N1_ITPKA from Dr. Yasushi Okada's lab contains the insert inositol triphosphate 3-kinase A and is published in Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4352-6. doi: 10.1073/pnas.1418468112.

ITPKA Gene Body Methylation Regulates Gene Expression and Serves as an Early Diagnostic Marker in Lung and Other Cancers. Wang YW, Ma X, Zhang YA, Wang MJ, Yatabe Y, Lam S, Girard L, Chen JY, Gazdar AF

IP3-3KA, IP3KA. Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. ITPKA gene body displayed low or absent levels of methylation in most normal tissue but was significantly methylated in malignant tumors. In lung cancer, ITPKA gene body methylation first appeared at the in situ carcinoma stage and progressively increased after invasion. Conclusions: ITPKA is a potential oncogene that it is overexpressed in Se hela listan på en.wikipedia.org 2021-03-02 · ITPKA is a potential oncogene that it is overexpressed in most tumors, and its overexpression promotes tumorigenesis; ITPKA gene body methylation regulates its expression and serves as a novel and potential biomarker for early cancer detection ITPKA (Inositol-Trisphosphate 3-Kinase A) is a Protein Coding gene. Among its related pathways are superpathway of inositol phosphate compounds and Metabolism .

Wide variety of Top suppliers High-quality customer support. Symbol: Itpka: Name: inositol-trisphosphate 3-kinase A: RGD ID: 619950: Description: Exhibits Rac GTPase binding activity; calmodulin-dependent protein kinase activity; and inosit ITPKA Antibodies Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.